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NCT Number (or ClinicalTrials.gov Identifier)

See ClinicalTrials.gov Identifier (NCT Number).

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Multiple-Center Trial/Study

A clinical trial conducted according to a single protocol but at more than one site and therefore carried out by more than one investigator. (Pfizer)

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Monitoring

The act of overseeing the progress of a clinical study, and ensuring that it is conducted, recorded, and reported in accordance with the protocol, Standard Operating Procedures (SOPs), Good Clinical […]

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Monitor

Individual who acts as a liaison between the sponsor and the investigator of a clinical study, and who oversees the progress and conduct of the trial; may also be referred […]

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Material Transfer Agreement (MTA):

A contract, generally without funding, which provides a legal framework to govern the exchange of research materials between academic, government, and commercial organizations. The types of materials transferred under MTAs […]

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Masking (blinding)

A clinical trial design strategy in which one or more parties involved with the trial, such as the investigator or participant, do not know which participants have been assigned which […]

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Last Verified Date

The last verified date is the most recent date that all of a clinical study’s information on ClinicalTrials.gov was confirmed as accurate and up to date. This date may be […]

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Last Updated

The last updated date is the most recent date that changes to study information were submitted to ClinicalTrials.gov. There may be a delay of a few weeks before the updated […]

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Kefauver-Harris Amendments

In 1962, the Kefauver-Harris Amendments were enacted to the Food, Drug and Cosmetic Act of 1938. These amendments address the protection of human subjects in clinical research and required the […]

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Investigator Site File

The master file containing essential trial documents residing at the investigational site. (Pfizer)

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